Fission yeast NDR/LATS kinase Orb6 regulates exocytosis via phosphorylation of the exocyst complex
Sawin lab paper featured in Cell Rep.
Authors
Tay YD, Leda M, Spanos C, Rappsilber J, Goryachev AB, Sawin KE
Summary
NDR/LATS kinases are known primarily for their role in controlling cell and tissue proliferation and morphogenesis, e.g. via regulation of transcription in the Hippo pathway. Using fission yeast S. pombe as a model system, Tay et al. show that the NDR/LATS kinase Orb6 is a major regulator of exocytosis.