Oligomerization of Drosophila Nucleoplasmin-like protein is required for its centromere localization
Heun lab paper featured in Nucleic Acids Research.
Authors
Anselm, E., Thomae, A.W., Arocia Jeyaprakash, A., Heun, P
Summary
The Nucleoplasmin Like Protein, NLP and its paralog NPH (brown) form a hetero-pentamer that co-localises with clusters of centromeres in Drosophila. STED superresolution microscopy revealed that NLP (green) and different centromeres (red) form distinct domains with little overlap allowing unprecedented insights into the substructure of centromere clusters.