High-resolution mapping of centromeric protein association using APEX-chromatin fibers
Heun lab paper featured in Epigenetics & Chromatin.
Authors
Kyriacou, E., Heun, P.
Summary
The centromere is a specialised chromosomal locus that forms the kinetochore and ensures faithful chromosome segregation. In this paper, we present a novel microscopy-based approach called “APEX-chromatin fibers” for localising protein binding over the repetitive centromeric sequences at kilobase resolution.