Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation
Heun lab paper featured in the Journal of Cell Biology.
Authors
Bobkov, G.O.M., Gilbert, N., Heun, P.
Summary
Transcription is important for the loading of the epigenetic centromere mark CENP-A, yet its role remains unclear. In this study, we report that transcription-mediated chromatin remodelling enables the transition of centromeric CENP-A from chromatin association to full nucleosome incorporation.