Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition
Jeyaprakash lab paper featured in EMBO reports.
Authors
Spiller, F., Medina-Pritchard, B., Abad, M.A., Wear, M.A., Molina, O., Earnshaw, W.C., Jeyaprakash, A.A.
Summary
The cell cycle‐dependent assembly of the Mis18 complex is essential for HJURP‐mediated CENP‐A deposition at centromeres. This study presents the molecular basis for how the Mis18 complex is assembled and how Cdk1 times the assembly.