The kinetochore prevents centromere-proximal crossover recombination during meiosis
Marston lab paper featured in eLife.
Authors
Vincenten N, Kuhl LM, Lam I, Oke A, Kerr AR, Hochwagen A, Fung J, Keeney S, Vader G, Marston AL.
Summary
This study shows that the kinetochore and the cohesin-rich pericentromere spatially control meiotic recombination thereby providing the first molecular evidence for the long-observed phenomenon of crossover suppression near centromeres.