Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes
Earnshaw lab paper featured in the Journal of Cell Biology.
Authors
Platani, M., L. Trinkle-Mulcahy, M. Porter, A.A. Jeyaprakash and W.C. Earnshaw
Summary
This paper shows that the important kinase mTOR has an important role in regulating the activation of Aurora A and Plk1 kinases at mitotic centrosomes. This is the first evidence for a role of mTOR in mitosis.