Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis
Ohkura lab paper featured in Development.
Authors
Colombié N, Cullen CF, Brittle AL, Jang JK, Earnshaw WC, Carmena M, McKim K, Ohkura H
Development 135, 3239-3246
Summary
In many animals including humans during female meiosis spindle formation takes place independently of centrosomes. Chromosomes play a central role in spindle assembly. In this article the Ohkura lab uses live imaging to demonstrate that the chromosomal passenger protein Incenp has a role in acentrosomal spindle formation.