Wellcome Trust Clinical Research Facility

The Wellcome Trust Clinical Research Facility provides dedicated facilities and specialist nursing support for a wide range of clinical studies.

The Wellcome Trust Clinical Research Facility (WTCRF) at the Western General Hospital provides dedicated facilities and specialist nursing support for a wide range of clinical studies, including the CGEM led Cystic Fibrosis Gene Therapy trial. The WTCRF Genetics Core is co-directed by CGEM Professors Tim Aitman and David Porteous providing close links and facilitating numerous research and clinical collaborations across CGEM.

The WTCRF Genetics Core also provides services externally, and is staffed and equipped to provide secure receipt, processing, archiving and analysis of biological samples. With well-defined Standard Operating Procedures and sophisticated automation the WTCRF Genetics Core offers a high quality and high throughput capability to assist researchers. Services include:

• DNA extraction from blood and mouthwash
• Peripheral Blood Lymphocyte isolation
• Plasma and Serum isolation
• Sample storage with barcode registration and sample inventory
• DNA quantification and normalisation
• Genetic Analysis including SNP Genotyping and Gene expression
• Methylation analysis
• Next generation DNA sequencing

For further information please visit the WTCRF.

Further information on the Cystic Fibrosis Gene Therapy trial.