Yuxiao Chen

Visiting Student, Centre for Regenerative Medicine (CRM), Institute for Regeneration and Repair, University of Edinburgh

Background

2025: Visiting Student, Soufi Group, Centre for Regenerative Medicine (CRM), Institute for Regeneration and Repair (IRR), The University of Edinburgh

2023–Present: Undergraduate Research Student, Cell Fate Control Lab (Prof. Duanqing Pei), Westlake University

2023–2027 (Expected): BSc in Biology (in progress), Westlake University, China

Research summary

3D Genome Architecture — Investigating how higher-order chromatin organization contributes to the regulation of cell fate, with a particular focus on major satellite (MajSat) clustering and its role in stabilizing pluripotent genome structure.

Chromatin Accessibility — Exploring how chromatin regulators and transcription factors shape accessible regulatory landscapes to control gene networks.

Totipotency–Pluripotency Transition — Studying the mechanisms by which totipotent loci are released from repressive structures, and developing approaches to reset pluripotent cells into totipotent-like states.