Dr Takanobu Tagawa
Research Fellow
Contact details
- Email: Takanobu.Tagawa@ed.ac.uk
Background
Wellcome Trust Career Development Award Research Fellow (2024-2030)
Postdoctoral fellow (2017-2023)
Joseph Ziegelbauer Lab, HIV and AIDS Malignancy Branch, National Cancer Institute, USA
Doctoral Student (2011- 2017)
Wolfgang Hammerschmidt Lab, Research Unit Gene Vectors, Helmholtz Center Munich, Germany
Master Student (2009 - 2011)
Hideo Iba Lab, The Institution of Medical Science, University of Tokyo, Japan
Research Assistant (2007 - 2009)
Yuichi Iino Lab, Molecular Genetics Research Laboratory, Department of Biophysics and Biochemistry, University of Tokyo, Japan
CV
149792.pdf
Qualifications
Doctoral degree (Dr. rer. nat, Ph.D. equivalent) in Biology (2011-2016)
Ludwig-Maximilians-University, Munich, Germany
Master of Science in Biology (2009-2011)
University of Tokyo Graduate School, Tokyo, Japan
Bachelor of Science (2005-2009)
University of Tokyo, Department of Biophysics and Biochemistry (Major)
Undergraduate Program for Bioinformatics and Systems Biology (Minor)
Responsibilities & affiliations
Undergraduate teaching
Postgraduate teaching
Areas of interest for supervision
Current PhD students supervised
Past PhD students supervised
Research summary
Circular RNA is a novel regulator of virus infection. They are abundant RNA species in human cells and interact with other RNAs and proteins to regulate cellular physiology. The Tagawa lab aims to define functions and mechanisms of non-coding RNAs in virus-host interactions. We are among the first to identify virus infection-induced circular RNAs and to discover herpesvirus-encoded circular RNAs. Using tumour-associated human herpesviruses including Epstein-Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV), we found a human circular RNA, circRELL1, that can suppress viral lytic cycle, a process that produces new virions and spread infection. Still, circRELL1 is one of many host circular RNAs that are commonly induced by multiple herpesviruses and we also discovered virus-encoded circular RNAs of unknown functions.
Knowledge exchange
Affiliated research centres
Project activity
Conference details
Invited speaker
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Papers delivered
In the press