Ramon Grima

Biography

Background

2000               B. Sc (Hons), Physics and Pure Mathematics, University of Malta, Malta

2002               M.A. Physics, University of Virginia, USA

2005               Ph.D Physics, Arizona State University, USA

2005-2006    Postdoctoral Fellow, School of Informatics, Indiana University, US

2006-2008    Mathematical Institute Fellow, Imperial College London

2008-2013    Lecturer, University of Edinburgh

2013-2019    Reader, University of Edinburgh

2019-              Professor University of Edinburgh

Undergraduate teaching

Quantification in Life Sciences (Course Organizer)

Structures and Functions of Proteins

Research summary

http://grimagroup.bio.ed.ac.uk/

My research is focused on the exact or approximate solution of the chemical master equation describing biochemical systems, with a particular focus on gene regulatory networks. I am also interested in the approximate solution of the reaction-diffusion master equation and its extension to take into account the complex nature of the cytoplasm e.g. phenomena such as macromolecular crowding. A main aim is to obtain closed-form solutions for the approximate distributions of molecule numbers (or of the moments) which can help us gain intuition about stochastic intracellular dynamics, in particular to understand how living cells have evolved to deal with inherent noise. More recently I have a burgeoning interest in developing efficient methods for the estimation of parameter values for gene regulatory networks from single cell and population snapshot data.

 

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