Professor Brian Bigger
Chair of Advanced Therapeutics
- Centre for Regenerative Medicine
- Institute for Regeneration and Repair
Contact details
- Email: brian.bigger@ed.ac.uk
Address
- Street
-
Centre for Regenerative Medicine
Institute for Regeneration and Repair
Edinburgh BioQuarter
5 Little France Drive - City
- Edinburgh
- Post code
- EH16 4UU
Background
Brian Bigger graduated from Bath University with a degree in Applied Biology and later a PhD in gene therapy from Imperial College London. Brian set up the Stem Cell & Neurotherapies group at the University of Manchester in 2006 to understand pathology and develop treatments for neurological lysosomal storage disorders, essentially childhood dementias. His group was the first to separate lysosomal storage from neuro-inflammation and show the role of both processes in the pathology of neurological lysosomal diseases. His lab developed several gene and cell therapy treatments for lysosomal diseases including three clinical trials.
Brian moved to the University of Edinburgh in 2023 to take up a Chair in Advanced Therapeutics at the Institute for Regeneration and Repair and retains an Honorary Chair in Cell and Gene Therapy at the University of Manchester. The Bigger lab continues to develop innovative gene and cell therapies for neurological diseases, including lysosomal diseases and bring these treatments to patients.
Qualifications
PhD Imperial College 2000
BSc University of Bath 1995