Poppy Zenzi Grimes (MSc, BSc)
Thesis title: Genetic and Symptom Heterogeneity in Adolescent Depression

MRC Precision Medicine Doctoral Training Programme
Year of study: 3
- Division of Psychiatry
- Centre for Clinical Brain Sciences
Contact details
- Email: p.grimes@ed.ac.uk
- Web: Google Scholar
- Web: ORCID
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PhD supervisors:
Address
- Street
-
Chancellor's Building
Edinburgh BioQuarter
49 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4SB
Background
MSc Neuroscience - University of Sussex (2020-2021)
BSc Biology - University of Sussex (2016-2020)
Postgraduate teaching
MSc Introduction to Genetic and Molecular Epidemiology
Conference details
World Congress of Psychiatric Genetics, Singapore, 2024: Symposium speaker
World Congress of Psychiatric Genetics, Montreal, Canada, 2023: Poster presentation
Autism Europe, International Congress, Krakow, Poland 2022: 2x Poster presentation
American Psychosomatic Society, Annual Meeting, Long Beach, California 2022: Poster presentation
Grimes PZ, Mitchell BL, Thompson KN....Whalley HC % Kwong ASF (2025). Genome-wide association study of adolescent-onset depression. medRxiv. https://doi.org/10.1101/2025.09.26.25335972
Skelton M, Mitchell BL, Assary E....Grimes PZ....& Eley TC (2025) Genome-wide insights into generalised anxiety using a dimensional symptom severity approach. medRxiv. https://doi.org/10.1101/2025.07.10.25331321
Thomas JT, Thorp JG, Huider F, Grimes PZ....& Mitchell BL (2025) Sex-stratified genome-wide association meta-analysis of Major Depressive Disorder. Nature Communications. https://doi.org/10.1038/s41467-025-63236-1
Xu EY, Grimes PZ, Kwong ASF, Lawrie SM & Whalley HC (2025). Longitudinal Prediction of Adolescent Depression from Environmental and Polygenic Risk Scores. medRxiv. https://doi.org/10.1101/2025.07.08.25331098
Grimes PZ, Murray AL, Smith K, Allegrini AG, Piazza GG, Larsson H, Epskamp S, Whalley HC & Kwong ASF (2025). Network temperature as a metric of stability in depression symptoms across adolescence. Nature Mental Health. https://doi.org/10.1038/s44220-025-00415-5
Grimes PZ, Adams MJ, Thng G, Edmonson-Stait AJ, Lu Y, McIntosh A, Cullen B, Larsson H, Whalley HC & Kwong ASF (2024). Genetic Architectures of Adolescent Depression Trajectories in 2 Longitudinal Population Cohorts. JAMA psychiatry. https://doi.org/10.1001/jamapsychiatry.2024.0983
Grimes PZ, Kampoureli CN, Rae CL, Harrison NA, Garfinkel SN, Critchley HD & Eccles JA (2023). The Neural Correlates of Autonomic Interoception: Perceptual Mismatch and Clinical Implications. medRxiv, 2023-05. https://doi.org/10.1101/2023.05.25.23290230
Eapen V, Karlov L, John JR, Beneytez C, Grimes PZ, Kang YQ, ..... & Volgyesi-Molnar M (2023). Quality of life in parents of autistic children: A transcultural perspective. Frontiers in psychology, 14, 684. https://doi.org/10.3389/fpsyg.2023.1022094