Pierre Bagnaninchi

Biography

Background

Dr Pierre-Olivier Bagnaninchi is a principal investigator at the College of Medicine and Veterinary Medicine (CMVM), at the University of Edinburgh (UoE).

Pierre-Olivier studied theoretical physics (MSc, 97) before moving to the field of biomedical engineering. He obtained his PhD in biomedical engineering in 2001 from the University of Grenoble, France in partnership with Thales optoelectronics. He then joined Prof. Maryam Tabrizian's lab at McGill University to develop impedance-based biosensors for tissue engineering applications. In 2004, he joined the Institute of Science and Technology for Medicine at Keele University (UK) under the supervision of Prof. Alicia El Haj and Professor Ruikang Wang to develop a polarization-sensitive optical coherence tomography system. In 2008 he was awarded a 5-year RCUK fellowship at the University of Edinburgh to develop, as an independent researcher, novel label-free technologies to measure cell and tissue physical properties with applications in regenerative medicine.

Pierre Bagnaninchi is a guest professor at Nanjing University of Aeronautics and Astronautics since November 2022.

 

Publications on Google scholar: https://scholar.google.co.uk/citations?hl=en&user=JpB-ZcgAAAAJ&view_op=list_works&sortby=pubdate 

ORCID profile: https://orcid.org/0000-0001-5433-9630

Open to PhD supervision enquiries?

Yes

Research summary

Our main research interest is the development of label-free quantitative technologies to map biophysical properties (mechanical, optical, flow, electrical) of cells and tissues. They also address the need for real-time monitoring of 3D (spheroids, organoids) in vitro disease models, and the need to monitor tissue repair in pre-clinical studies. To this end, we currently investigate optical coherence tomography, impedance sensing and their combination into organ-on-a chip technologies with a focus on ophthalmological applications.

We currently have projects on:

  1. Optical coherence tomography for tissue engineering and regenerative medicine 
    1. Measuring the mechanical properties of cells and tissues by optical means
  2. Noninvasive biosensors and quantitative methods in medicine and biology:
    1.  Label-free Impedance-based cellular assays (ECIS, EIT)
    2. Label-free 3D optical toxicity assays
  3. Organ-on-a-chip models of age-related macular degeneration

Publications on Google scholar: https://scholar.google.co.uk/citations?hl=en&user=JpB-ZcgAAAAJ&view_op=list_works&sortby=pubdate 

ORCID profile: https://orcid.org/0000-0001-5433-9630

 

  • EPSRC
  • BBSRC
  • European Union Horizon
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