Otto-Emil Jutila (BSc (Hons) , MSc(Oxon))

Thesis title: Air pollution and Dementia: Exploring genetic, cardiovascular, and epigenetic moderators and mechanisms

Precision medicine

Year of study: 3

  • Karolinska Institute
  • Alzheimer Scotland Dementia Research Centre
  • University of Glasgow

Contact details

Background

I am a Ph.D. student in Precision Medicine at the University of Edinburgh, where my research focuses on investigating the impact of air pollution on dementia risk and uncovering the underlying mechanisms. My research interests include omics, genetics, twin studies, life course epidemiology, and biological aging.

 

Publications

Jutila OI, Mullin D, Vieno M, Tomlinson S, Taylor A, Corley J, Deary IJ, Cox SR, Baranyi G, Pearce J, Luciano M, Karlsson IK, Russ TC. Life-course exposure to air pollution and the risk of dementia in the Lothian Birth Cohort 1936. Environ Epidemiol. 2024 Dec 10;9(1):e355. doi: 10.1097/EE9.0000000000000355

Farina FR, Bridgeman K, Gregory S, Crivelli L, Foote IF, Jutila OI, Kucikova L, Mariano LI, Nguyen KH, Thayanandan T, Akindejoye F, Butler J, Calandri IL, Čepukaitytė G, Chiesa ST, Dawson WD, Deckers K, Cruz-Góngora V, Dounavi ME, Govia I, Guzmán-Vélez E, Heikal SA, Hill-Jarrett TG, Ibáñez A, James BD, McGlinchey E, Mullin DS, Muniz-Terrera G, Pintado Caipa M, Qansuwa EM, Robinson L, Santuccione Chadha A, Shannon OM, Su L, Weidner W, Booi L. Next generation brain health: transforming global research and public health to promote prevention of dementia and reduce its risk in young adult populations. Lancet Healthy Longev. 2024 Dec;5(12):100665. doi: 10.1016/j.lanhl.2024.100665

Hodgson JR, Benkowitz C, Castellani BC, Ellison A, Yassaie R, Twohig H, Bhudia R, Jutila O-EI, Fowler-Davis S. A Scoping Review of the Effects of Ambient Air Quality on Cognitive Frailty. Environments. 2024; 11(1):4. https://doi.org/10.3390/environments11010004

Boo YY, Jutila OE, Cupp MA, Manikam L, Cho SI. The identification of established modifiable mid-life risk factors for cardiovascular disease which contribute to cognitive decline: Korean Longitudinal Study of Aging (KLoSA). Aging Clin Exp Res. 2021;33(9):2573-2586. DOI: 10.1007/s40520-020-01783-x

 

Qualifications

MSc in Global Health Science and Epidemiology, University of Oxford, UK

BSc in Biomedical Science, Robert Gorden University, UK

 

Research summary

AIr pollution and dementia,  what is the relationship and the underlying pathways.

Affiliated research centres

Papers delivered

Jutila OEI, Baranyi G, Cox SR, Luciano M, Russ TC, Karlsson IK. Life course air pollution exposure and later-life risk of all-cause and cardiovascular specific mortality in the Lothian Birth Cohort 1936. ISEE Conference Abstracts. 2024;2024(1)https://doi.org/10.1289/isee.2024.1664

 

Jutila, O.-E.I., Welstead, M., Mullin, D.S., Tomlinson, S., Vieno, M., Cox, S.R., Baranyi, G., Russ, T.C., Luciano, M. and Karlsson, I.K. (2023), Life course exposure to air pollution and the risk of mild cognitive impairment and dementia in the Lothian Birth Cohort 1936. Alzheimer's Dement., 19: e079774. https://doi.org/10.1002/alz.079774