Professor Neil Mabbott

Personal Chair of Immunopathology

Tel: 0131 651 9113
Fax: 0131 651 9105
Email: neil.mabbott@roslin.ed.ac.uk
Web: University of Edinburgh Research Explorer Profile
Web: Google Scholar Profile

Street: The Roslin Institute
Easter Bush Campus
Midlothian
City
Post code: EH25 9RG

Willingness to take Ph.D. students: Yes

Biography

Background

1989-1992, BSc (Hons) Microbiology, University of Leeds, UK

1992-1995, PhD Immunoparasitology, University of Aberdeen, UK

1995-2003, Post-doc, Neuropathogenesis Unit, Institute for Animal Health, Edinburgh UK

2003-2005, Senior post-doc, Neuropathogenesis Unit, Institute for Animal Health, Edinburgh UK

2006-2007, Principal scientist, Neuropathogenesis Unit, Institute for Animal Health, Edinburgh UK

2007-2009, Principal scientist, The Roslin Institute, Edinburgh UK

2009-2015, Reader, The Roslin Institute & Royal (Dick) School of Veterinary Studies, Edinburgh UK

2015-present, Professor, Personal Chair in Immunopathology, The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, UK

2021-present, Director of Teaching (The Roslin Institute), The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, UK

2023-present, Head of the Immunology Division, The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, UK

Qualifications

Doctor of Philosophy (PhD), University of Aberdeen, Nitric oxide, friend or foe during trypanosomiasis?

Bachelor of Science (BSc hons), Microbiology, University of Leeds

Research

Research summary

Host-pathogen interactions in the mucosal immune system.

Current research interests

My research aims to understand the pathogenesis of infectious diseases within the immune system. Particular interests include understanding host-pathogen interactions within the mucosal immune system, especially prion diseases and other gastrointestinal pathogens such as Salmonella and nematodes. Studies are also focused on the effects of host age on the function of the immune system and how this influences susceptibility to gastrointestinal pathogens. A systems biology approach is also being used to compare the transcriptomic profiles of distinct immune cell populations in the steady-state, and also during ageing. This research benefits greatly from the availability of precisely defined mouse prion pathogenesis models, unique transgenic and immunodeficient mice and state-of-the-art bio-imaging and bioinformatics expertise.