Horace Chan

Thesis title: Defining novel targets to enhance neovascularisation & lymphangiogenesis in the ischaemic heart

Biography

Background

PhD candidate supported by the MRC/BHF REACT grant and affiliated to the Precision Medicine DTP programme. I am interested in contributing to the translation of ATMPs/regenerative medicine from bench to bedside. On the research side, my current project aims to discover and validate novel targets to promote cardiac vessel growth after heart attacks for nucleic acid therapy development. On the non-research side, I am involved in PRIMED Edinburgh, an ARIA & venture-backed initiative that aims to develop a local community of commercialisation-savvy early career researchers in deep tech.

Qualifications

MScR, Regenerative Medicine & Tissue Repair (University of Edinburgh)

Current research interests

My PhD aims to define novel targets that enhances neovascularisation and lymphangiogenesis in the heart after myocardial infarction (MI). The initial phase of this project focuses on target discovery. Through bioinformatic analysis on transcriptomic datasets and high throughput screening on endothelial cell lines, the key output will be nucleic acid candidates (target genes/microRNA) that can augment blood and lymphatic vessel growth simultaneously.

Affiliated research centres

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