Dr Douglas Gibson
Sir Henry Dale Fellow
- Centre for Reproductive Health
- Centre for Inflammation Research
- Institute for Regeneration and Repair
Contact details
- Email: d.a.gibson@ed.ac.uk
Address
- Street
-
Institute for Regeneration and Repair
The University of Edinburgh
Edinburgh BioQuarter
4-5 Little France Drive - City
- Edinburgh
- Post code
- EH16 4UU
Background
I obtained my undergraduate degree in Pharmacology from the University of Edinburgh before undertaking a PhD at the MRC Human Reproductive Sciences Unit with Professor Philippa Saunders examining the role of estrogen signalling in the endometrium. I undertook postdoctoral training at the MRC Centre for Reproductive Health and then the MRC Centre for Inflammation Research where I discovered that local hormone signalling within the endometrium was required for establishment of pregnancy in women.
These studies attracted significant media attention (The Times, The Sun, The Daily Mail) and were recognised by the award of the Society for Endocrinology Early Career Lecture Prize (2018) and the Society for Reproduction and Fertility New Investigator Award 2020.
In July 2020, I was awarded a Royal Society and Wellcome Trust Sir Henry Dale Fellowship to establish my own laboratory in Edinburgh investigating the impact of androgens on macrophage function during endometrial tissue repair.
Open to PhD supervision enquiries?
Yes
Research summary
My research is focussed on understanding the mechanisms that regulate endometrial function and how these can become dysregulated in common reproductive disorders that affect millions of women.
I investigate how signalling molecules called hormones can act within tissues to change the function of key cell types that are important for fertility and reproductive function.
Current research interests
My research focuses on understanding how hormones, particularly androgens, control immune cell function in the womb and how this might affect women's reproductive health. My lab uses fate-mapping techniques, transcriptomics analysis, multiparameter flow cytometry and immunohistochemistry in order to characterise the phenotype and function of immune cell populations that are required for endometrial repair and remodelling.Affiliated research centres
Current project grants
2023 – 2024 MRC Impact Acceleration Award. (PI)
2022 – 2026 MRC Precision Medicine DTP PhD studentship (PI)
2021 – 2026 Royal Society and Wellcome Trust Sir Henry Dale Fellowship (PI)
2020 – 2024 EASTBIO BBSRC DTP 4-year PhD project (Co-Investigator)
Past project grants
2022 – 2023 Wellcome Trust Institutional Translational Partnership Award (PI)
2021 – 2023 Medical Research Scotland ECR grant (PI)
2020 – 2022 Wellcome-Beit Prize (PI)
2016 – 2021 MRC programme grant 2016-2021 (Co-Investigator)
2015 – 2016 Society for Endocrinology Early Career Grant (PI)
2022 Elected to the Young Academy of Scotland
2021 Institute for Regeneration and Repair Early Career Innovator prize
2021 Society for Endocrinology Leadership & Development Award
2020 Wellcome-Beit Prize
2019 Society for Reproduction and Fertility New Investigator Award
2018 Society for Endocrinology Early Career Prize lecture
2018 Scottish Crucible