Dr. Alejandro J. Brenes

Postdoctoral Computational Biologist - Granulocyte Proteomics

Biography

Background

Alejandro graduated from his PhD at the University of Dundee in 2023 under the supervision of Prof. Cantrell and Prof. Lamond. His work focussed on using large-scale proteomics and computational biology to characterise the murine and human immune system, with a focus on murine T cells and human neutrophils. This led him to create the Immunological Proteome Resource (immpres.co.uk).

In 2024 Alejandro started working as a postdoctoral computational biologist within the Walmsley Group at the Centre for Inflammation Research, part of the University of Edinburgh. His research is now focussed on the proteomic characterisation of human granulocytes by leveraging mini-bulk and single cell proteomic workflows with the aim to define their functional heterogeneity, functional capacities and phenotypes in both homeostasis and chronic inflammatory disease.

Responsibilities & affiliations

British Society for Proteome Research Management Committee

British Mass Spectrometry Society

British Society for Immunology

Research summary

Alejandro's research area is systems immunology and proteomics. He aims to leverage cutting edge mass spectrometry-based proteomics methods, including mini-bulk and single cell proteomics, combined with computational and AI developments in order to characterise human granulocytes.

Alejandro's research interest also focus on open data and data sharing, attempting to make the processed proteomics data easily available as a community resource. He is the creator and maintainer of the Immunological Proteome Resource (http://immpres.co.uk/).

Affiliated research centres

Invited speaker

11th in-person Lodon Proteomics Discussion Group Symposium (2024)

5th European Symposium on Single Cell Proteomics (2024)

Scottish Biological Mass Spectrometry Meeting (2023) 

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