Dr A. Garcia-Dominguez

Royal Society University Research Fellow

Research summary

Isotope labelling, Catalysis, Chemical Reactivity, Reaction Monitoring, Organometallics, Organofluorine.

Research overview

At the core of our research is the mechanistically informed design of new chemical reagents and catalytic strategies using reaction monitoring techniques and kinetic analyses. In particular, we seek to unlock the potential of organosilicon and organoboron chemistry to afford common platforms for the selective preparation/degradation of a diversity of organofluorine chemicals and isotopically enriched molecules.

Expertise: Isotope labelling; deuteration; reaction mechanisms; isotope effects; catalysis; reaction kinetics; reaction monitoring; NMR spectroscopy; nickel-catalysis; silicon chemistry; organometallics

Sectors: Catalysis, Analysis, Isotope Chemistry, Synthesis & Manufacture

The García-Domínguez group specializes in two areas: 1) Reaction mechanisms: we use a combination of experimental physical organic chemistry approaches to explain why chemicals behave the way they do, and use that information to guide improved chemical processes. We have experience investigating the reactivity of silicon, organic, phosphorus, boron and sulfur chemicals; as well as organic and organometallic catalysis. 2) Isotope labelling: we develop strategies to introduce non-radioactive isotopes in specific sites within organic, inorganic and organometallic chemicals. Isotopes that we work with include, but are not limited to: deuterium, 13Carbon, 15N, Boron-isotopes. The group has established a partnership with Syngenta to understand the reactivity of Nickel catalysts, and has previously collaborated with Eastman and Flexsys providing useful insights into sulfur chemistry.

 

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