Dr Clémence Fraslin

Research Fellow - Aquaculture Breeding

Biography

Background

I am a quantitative geneticist working in various fish species on trying to understand the genetic architecture of complex traits, mainly disease resistance traits, and breeding fish for more sustainability.  My work focuses mainly on salmonids (Atlantic salmon and rainbow trout) but I have also worked on other species including Nile tilapia, Tiger pufferfish and Atlantic halibut. 

I studied Agricultural productions in France at AgroParisTech (Paris, France) before completing a PhD in Animal Genetics at INRAe (France) on the genetic determinism of rainbow trout resistance to Flavobacterium psychrophilum.

  • [2022-Present]  Core Scientist in the Robledo's group
  • [2019-2022]         Postdoctoral Research Fellow (The Roslin Institute)
  • [2018-2019]         Postdoctoral Research Fellow (INRAe)
  • [2015-2018]         PhD in Animal Genetics (INRAe, Université De Paris Saclay)

Qualifications

PhD in Animal Genetics from Université de Paris Saclay, AgroParisTech, INRAe (France)

Open to PhD supervision enquiries?

Yes

Research summary

My main interest is to understand the genetic architecture and differences that drives responses to pathogens in aquaculture species.

I use quantitative genetics and genomics approaches  to understand differences in resistance / susceptibility and learn about the genomic mechanisms underpinning  immune responses. I also use different approached to predict the genetic merit of farmed fish.

The final goal  is to exploit this knowledge to select for disease resistant animals through genomic selection.

To learn more about the research of the aquaculture genetics group at the Roslin Institute, visit https://www.ed.ac.uk/roslin/aquaculture

Current research interests

My main interest if how to improve genomic selection of farmed fish. Using different models to increase the accuracy of our prediction. I am interested at how we can make genomic selection affordable using low-density SNPs array and imputation. I am also interested in better understanding the genetic architecture of resistance traits and for that I am using whole-genome sequence, combined with phenotype and genotype dataset to detect candidate genes that could be involved in resistance mechanisms.

Current project grants

Title: Genomic tools for an improved sustainability of Scottish Halibut
Funded by: Scottish Universities Life Science Alliance
PI: Fraslin, C.
05/24 → 04/25

Title: IDG 2023/28 - 2024 - Connectivity- Promoting collaboration and innovation in computational genetics at the Roslin Institute through extension of the Computational Genetics Discussion Group seminar series
Funded by: BBSRC
PI: Fraslin, C., Becher, H. & Rochus, C.
07/24 →03/25

Title: Sustainable aquaculture partnerships for innovation”. Accelerating genetic improvement of Atlantic salmon using speed breeding and gene editing technologies
Funded by: UKRI/BBSRC
PI: Robeldo D., McGrew M.
Co-Researcher: Fraslin C.

Title: Integrative breeding strategies for the transition of European Aquaculture towards sustainable Organic production
Funded by: Horizon Europe Framework Programme, call “Selective breeding programme for organic aquaculture”
PI: Robledo D., Wilson A., Fraslin C.,

Since 2022 I am a member of the CGDG, a seminar series in which we invite and host researcher to talk about computational genetics: https://www.youtube.com/channel/UCjFlQlYZzINXRawe13jc1mA 

 

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