Dr Ian MacCormick

Senior Clinical Lecturer

Background

Ian became interested in the microvasculature of the retina and brain, and how one might reflect the other, during medical school at Edinburgh.

During Ophthalmology training he had the privilege of studying retinal manifestations of paediatric cerebral malaria at the Malawi-Liverpool-Wellcome Trust. Paediatric cerebral malaria is an severe acute type of cerebral small vessel disease, a complication of severe P. falciparum malaria, and is the archetypal syndrome in which the retina 'mirrors the brain'. Working as part of a interdisciplinary team spanning Malawi, the UK and USA, Ian helped to show that in this syndrome retinal vessel leakage is very strongly associated with severe brain swelling and death. This research was recognized by the Royal College of Ophthalmologists in 2023 with the Ulverscroft award.

He returned to Edinburgh as a SCREDS lecturer in 2018, and continues to work on retinal biomarkers of brain disease and collaborative projects to translate clinical biology into algorithms.

Qualifications

BSc (Neuroscience), MBChB, PhD, FRCOphth

Responsibilities & affiliations

Ian is a Senior Clinical Lecturer at the University of Edinburgh, and Consultant Ophthalmologist at the Princess Alexandra Eye Pavilion, Edinburgh

He is a fellow of the Royal College of Ophthalmologists, and a registered specialist with the General Medical Council

Open to PhD supervision enquiries?

Yes

Current PhD students supervised

Jamie Burke (jointly with Stuart King and Kenny Baillie)

Nouhoum Diallo (Jointly with Alex Rowe)

Research summary

Ian's research interests include:

  • Retinal manifestations of systemic disease
    • Particularly disease of the CNS microcirculation, such as sporadic cerebral small vessel disease, severe malaria, diabetes
  • Understanding retinal variables as valid surrogates of systemic disease
    • Surrogate methodology
    • Causal inference
  • Analytical methods to convert retinal images into useful information about biology
    • Image segmentation
    • Using spatial data to infer spatial processes 

 

His publications can be found on Google Scholar and Pubmed:

https://scholar.google.com/citations?user=WgHmDd4AAAAJ&hl=en

https://www.ncbi.nlm.nih.gov/myncbi/1p19C6uMr5xAd/bibliography/public/

Affiliated research centres