Biological Sciences
Biological Sciences
Contact us

Events and seminars

CEB Seminar - Aditya Kunjapur, University of Delaware - "Engineering microbes to create and harness newer-to-nature building blocks"

Aditya Kunjapur (University of Delaware)

9th October 2025 at 12:00pm [Download iCalendar / .ics file]

CH Waddington Building, Seminar room 1.08

Abstract: Newer-to-nature building blocks such as non-standard amino acids (nsAA) can expand the repertoire of chemistries and functions that living systems can produce. However, reliance on chemical synthesis of nsAAs introduces several kinds of constraints that impact the costs and contexts where nsAAs can be used. In this talk, I will describe how biosynthesis of nsAAs can create new capabilities and safeguards for microbial engineering, including applications towards live vaccines or controlled release of microbes into the environment. I will also describe how one-pot semi-synthesis and incorporation of nsAAs within proteins can be an attractive alternative for industrial maturation of genetic code expansion (GCE) technologies in biomanufacturing, including a route for synthesis of encodable L-phenylalanine derivatives that we have developed in in cell-free and cellular formats. Overall, these research directions at the interface of metabolic engineering and chemical biology lay the groundwork for accelerating industrial adoption of, and unlocking new opportunities for, GCE for the benefit of human and planetary health.Engineering microbes to create and harness newer-to-nature building blocks | Centre for Engineering Biology | BiologyHiost: Stephen wallace
 

Host Centre for Engineering Biology (CEB)

iCalendar / ICS feed

Seminars are available in .ics format utilised by various calendar and email programs including Google Calendar, Apple iCal, and Microsoft Outlook.

RSS Feeds from Biology

Events and seminars are available via an RSS feed. Please click the link below to subscribe.

This article was published on